Research Project
Grant-in-Aid for Challenging Exploratory Research
To analyze ASK family-dependent stress signaling, we identified 55 candidate ASK activator candidates by a genome-wide RNAi screening in C. elegans. Those candidates were further analyzed in the context of neuronal differentiation, innate immunity and oxidative stress response. Finally, we identified gene X as an activator of ASK1 by comparing it with known p38signaling components.
All 2013 2012 2011 Other
All Journal Article (22 results) (of which Peer Reviewed: 22 results) Presentation (9 results)
Biochim. Biophys. Acta
Volume: 1830 Pages: 3656-3663
doi:10.1016/j.bbagen.2013.01.029
Am. J. Pathol
Volume: 182 Pages: 597-609
doi:10.1016/j.ajpath.2012.10.008
Adv. Biol. Regul., (review article)
Volume: 53 Pages: 135-144
doi:10.1016/j.jbior.2012.09.006
Cell Death Differ
Volume: 20 Pages: 270-280
doi:10.1038/cdd.2012.122
Nat. Commun.
Volume: 3 Pages: 1285
doi:10.1038/ncomms2283
Cancer Sci
Volume: 103 Pages: 2181-2185
Mol. Cell
Volume: 48 Pages: 692-704
doi:10.1016/j.molcel.2012.09.018
J. Biol. Chem
Volume: 287 Pages: 34635-34645
doi:10.1074/jbc.M112.357509
Proc. Jpn. Acad. Ser. B: Phys. Biol. Sci.,(review article)
Volume: 88 Pages: 434-453
doi:10.2183/pjab.88.434
J. Signal Transduc. (review article)
Volume: 2012 Pages: 12
doi:10.1155/2012/931215
Blood
Volume: 120 Pages: 1039-1047
doi:10.1182/blood-2011-12-399808
Int. J. Cell Biol., (review article)
Volume: 2012 Pages: 439587
doi:10.1155/2012/439587.
Ann. Neurol
Volume: 72 Pages: 739-749
doi:10.1002/ana.23668
Hypertens. Res
Volume: 35 Pages: 194-200
doi:10.1038/hr.2011.175
PloS ONE
Volume: 7 Pages: e30265
doi:10.1371/journal.pone.0030265
Volume: 7 Pages: e29935
doi:10.1371/journal.pone.0029935
Cell Death & Disease
Volume: 3 Pages: e261
doi:10.1038/cddis.2011.132
Am. J. Respir. Cell Mol. Biol.
Volume: 46 Pages: 461-469
doi:10.1165/rcmb.2011-0234OC
PLoS Pathogens
Volume: 7 Pages: e1002250
doi/10.1371/journal.ppat.1002250
Arterioscler. Thromb. Vasc. Biol
Volume: 31 Pages: 1555-1564
doi:10.1161/ATVBAHA.111.227140
J. Cell Sci
Volume: 124 Pages: 3006-3016
doi:10.1242/jcs.085902
Hepatology
Volume: 54 Pages: 185-195
doi:10.1002/hep.24357