2013 Fiscal Year Final Research Report
Screening of anti-tumor metastatic substances using salivary gland of blood feed animals and snake venom
| Project/Area Number |
23659216
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Parasitology (including Sanitary zoology)
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| Research Institution | Jichi Medical University |
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Principal Investigator |
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| Project Period (FY) |
2011 – 2012
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| Keywords | がん細胞 / 転移抑制 / 唾液腺 / 凝固阻害 / ルシフェリン / ルシフェラーゼ / ヒルジン / アスピリン |
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| Research Abstract |
Using a mouse colon cancer cell line (Colon26) I made screening for anti-tumor metastatic substances. Since Colon26 contains luciferase in the genome, you can monitor the cell grow by in vivo imaging system if the cancer cells grow in mouse body. The tested materials were mosquitoe salivary gland, salivary part of leech, hirudin (purified leech saliva), heparin and aspirin. Indeed I repeated the screening tests for several times, I failed to find anti-tumor metastatic substance.
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Research Products
(22 results)
