2012 Fiscal Year Final Research Report
A novel study elucidating risk of particulate matters using iPS
Project/Area Number |
23659337
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Research Category |
Grant-in-Aid for Challenging Exploratory Research
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Allocation Type | Multi-year Fund |
Research Field |
Hygiene
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Research Institution | International University of Health and Welfare |
Principal Investigator |
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Project Period (FY) |
2011 – 2012
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Keywords | 環境保健 |
Research Abstract |
At first, we examined in vitro assay conditions differentiating iPS toward cardiac cells such as myocytes and vascular endothelial cells , and developed condition differentiating iPS-derived myocytes. Next, we investigated the in vitro effects of diesel exhaust particle (DEP) -exposure on iPS-derived myocytes, and found that DEP tended to suppress pulsation of these cells as compared to vehicle-exposure.
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