2012 Fiscal Year Final Research Report
Intervention threshold for hip geometric indices according to the risk of hip fractures in Japanese women
| Project/Area Number |
23659362
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Public health/Health science
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| Research Institution | Kinki University |
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Principal Investigator |
IKI Masayuki 近畿大学, 医学部, 教授 (50184388)
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| Co-Investigator(Kenkyū-buntansha) |
SATO Yuho 仁愛大学, 生活学部, 准教 (10337115)
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| Project Period (FY) |
2011 – 2012
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| Keywords | 骨粗鬆症 / 大腿骨近位部骨折 / 骨構造解析 / リスク評価 |
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| Research Abstract |
e evaluated whether the hip structure analysis (HSA), a geometric assessment of the proximal femur, could be used to predict hip fracture risk in subsequent 15 years in Japanese women. We analyzed 1438 women who were aged 40 years and older at the time of the JPOS baseline study, whose HSA values were extracted from their hip DXA image obtained at baseline, and whose incidence of hip fracture during the 15 years of follow-up was determined. 36 women suffered from hip fractures. The section modulus at the narrow neck of the femur was significantly associated with hip fracture risk independently of age and estimated volumetric bone density (adjusted hazard ratio: 1.92 (95% confidence interval: 1.17, 3.14)). HSA indices may be used as a risk assessment method for hip fractures.
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