2011 Fiscal Year Final Research Report
Fibroblast pathology for suppression of inflammatory diseases
| Project/Area Number |
23659377
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
General internal medicine (including Psychosomatic medicine)
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| Research Institution | Tokyo Medical and Dental University |
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Principal Investigator |
KOHSAKA Hitoshi 東京医科歯科大学, 大学院・医歯学総合研究科, 准教授 (00251554)
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| Project Period (FY) |
2011
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| Keywords | 内科 / 線維芽細胞 / ケモカイン / 関節リウマチ / 筋炎 |
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| Research Abstract |
Although fibroblasts are activated in many inflammatory diseases, they are rarely targeted in treatment. The present studies were carried out to disclose pathological roles in inflammatory diseases. An isolation method of pathological fibroblasts has been established for analyses in arthritic diseases. Studies of regeneration processes involved in myositis revealed that chemokines are produced by mesenchymal cells.
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Research Products
(14 results)
