2013 Fiscal Year Final Research Report
Neural correlates of body dissatisfaction: A Functional MRI study.
| Project/Area Number |
23659390
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
General internal medicine (including Psychosomatic medicine)
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| Research Institution | University of Occupational and Environmental Health, Japan |
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Principal Investigator |
KODAMA NAOKI 産業医科大学, 医学部, 講師 (10352303)
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| Project Period (FY) |
2011 – 2013
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| Keywords | 摂食障害 / 体形の不満 / 機能画像 |
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| Research Abstract |
Eating disorders are disorders of unknown etiology that tend to affect young women. Body dissatisfaction is an important factor in anorexia nervosa (AN). However, the functional neuroanatomy of body dissatisfaction in AN is largely unknown. This study has investigated body-shape comparison to establish neural correlates of body dissatisfaction in patients with AN.
In the recovered AN group the body-shape comparison induced more activation of the left lingual gyrus, left fusiform body area and left amygdala when subjects compared their own body-shape with images of slim female bodies. The visual cortex responses reflect their concern about the bodies of others. Brain networks associated with anxiety that was induced by self-comparison to others' images may be involved in their hidden remaining body dissatisfaction and hence with the high relapse rate of eating disorders. The results are be helpful in that they shed light on the biological pathology of patients with eating disorders.
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