2012 Fiscal Year Final Research Report
Development of new technology for the analysis of and pharmacological effects on intracellular and intercellular conduction, using pulse-driven MI sensor operated at room temperature
| Project/Area Number |
23659397
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Gastroenterology
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| Research Institution | Nagoya University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
UCHIYAMA Tsuyoshi 名古屋大学, 工学研究科, 准教授 (00203555)
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| Project Period (FY) |
2011 – 2012
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| Keywords | 磁気センサー / 非侵襲 / 上部消化管 / ペースメーカー電流 / 再生医療 |
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| Research Abstract |
Magnetic sensors constructed with a magnetic amorphous wire surrounded by a pickup-coil, are referred to as MI sensor. In this study, a pair of MI magnetic sensors were operated by applying electric current through a CMOS inverter circuit, and were used as a gradio-sensor by using a differential amplifier circuit. During musculature preparations isolated from the gut of animals were superfused with an extracellular solution, and spontaneous magnetic waves were successfully recorded. In some experiments, electric field potentials were simultaneously recorded by suing extracellular electrodes along with magnetic waves.
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[Journal Article] Endogenous cardiac troponin T modulates Ca2+-mediated smooth muscle contraction2012
Author(s)
Kajioka S, Takahashi-Yanaga F, Shahab N, Onimaru M, Matsuda M, Takahashi R, Asano H, Morita H, Morimoto S, Yonemitsu Y, Hayashi M, Seki N, Sasaguri T, Hirata M, Nakayama S, Naito S
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Journal Title
Scientific Reports
Volume: 2
Pages: 979
URL
Peer Reviewed
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[Journal Article] Diphosphate regulation of ATP-sensitive potassium channel in human urinary bladder smooth muscle cells2011
Author(s)
Kajioka S, Shahab N, Asano,H, Morita H, Sugihara M, Takahashi-Yanaga F, Yoshihara T, Nakayama S, Seki N, Naito S
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Journal Title
Journal of Urology
Volume: 186
Pages: 736-744
Peer Reviewed
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