2012 Fiscal Year Final Research Report
Reconstitution of three-dimensional structures from the embryonickidney cells
| Project/Area Number |
23659446
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Kidney internal medicine
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| Research Institution | Kumamoto University |
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Principal Investigator |
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| Project Period (FY) |
2011 – 2012
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| Keywords | 腎臓学 / 腎臓発生 |
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| Research Abstract |
The embryonic kidney contains nephron progenitors, which interact with the ureteric budto differentiate into multiple lineages of the nephron. Upon establishment of the inducedpluripotent cells, many researchers aim at induction of nephron progenitors. However,induction of two-dimensional progenitors alone is not sufficient to regenerate the kidney.Therefore we tried to reconstitute the three-dimensional structures from the embryonicnephron progenitors, which will give us a hint toward the kidney regeneration
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