2012 Fiscal Year Final Research Report
Investigation of roles of miRNA in the immunosuppression and clinical use for patients with melanoma
| Project/Area Number |
23659554
|
|---|
| Research Category |
Grant-in-Aid for Challenging Exploratory Research
|
| Allocation Type | Multi-year Fund |
|---|
| Research Field |
Dermatology
|
|---|
| Research Institution | Keio University |
|---|
Principal Investigator |
|
|---|
| Co-Investigator(Kenkyū-buntansha) |
OHTA Shigeki 慶應義塾大学, 医学部, 講師 (20365406)
YAGUCHI Tomonori 慶應義塾大学, 医学部, 助教 (40424163)
|
|---|
| Co-Investigator(Renkei-kenkyūsha) |
AMAGAI Masayuki 慶應義塾大学, 医学部, 教授 (90212563)
KINIWA Yukiko 信州大学, 医学部附属病院, 講師 (20436893)
|
|---|
| Project Period (FY) |
2011 – 2012
|
| Keywords | 悪性黒色腫 / miRNA / 免疫逃避 / バイオマーカー |
|---|
| Research Abstract |
miR-222 is over-expressed in human melanoma cells, and may be a blood biomarker in melanoma patients because serum miR-222 is increased in patients particularly with advanced stage melanoma and metastasis. miR-222 may also be involved in the immunosuppres
|
-
-
-
-
-
-
-
-
-
-
-
-
[Book] The Tumor Immunoenvironment2013
Author(s)
Kawakami Y, Yaguchi T, Sumimoto H, Kudo-Saito C, Tsukamoto N, Iwata-Kajihara T, Nakamura S, Nishio H, Satomi R, Kobayashi A, Tanaka M, Kamijuku H, Tsujikawa T,KawamuraN
Total Pages
307-323
Publisher
Springer
-
-
[Book] Cancer-induced immunosuppressive cascades and their reversal by molecular-targeted therapy. Annals of the New York Academy of Sciences
Author(s)
Kawakami Y, Yaguchi T, Sumimoto H, Kudo-Saito C, Tsukamoto N, Iwata-Kajihara T, Nakamura S, Nishio H, Satomi R, Kobayashi A, Tanaka M, Hoon Park J, Kamijuku H, Tsujikawa T, and Kawamura N
Publisher
WILEY
-
