2012 Fiscal Year Final Research Report
Establishments of in vivo imaging technique for functional visualization ofadipose tissue and its potential application for diagnosis.
| Project/Area Number |
23659583
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Radiation science
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| Research Institution | Wakayama Medical University |
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Principal Investigator |
IHARA Hayato 和歌山県立医科大学, 共同利用施設, 講師 (00223298)
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| Co-Investigator(Kenkyū-buntansha) |
MAGATA Yasuhiro 浜松医科大学, メディカルフォトニクス研究所, 教授 (20209399)
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| Project Period (FY) |
2011 – 2012
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| Keywords | 生体イメージング / 脂肪組織 / 病態生理機能 / 可視化 |
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| Research Abstract |
Our studies focused not only on morphological changes in an increase of adipose-tissue weight and adipocyte size, but also on functional changes in gene expression and metabolism of adipose tissue. In this report, we tried to establish an in vivoimaging technique using an adipokine-reporter gene as indicator of adipose-functional changes. In the future, using this imaging technique, we may provide a useful index of diagnosis for patho-physiological aspects of increased adipose tissue
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[Journal Article] Comparison of Contrast Agents for Atherosclerosis Imaging Using Cultured Macrophages: FDG Versus Ultrasmall Superparamagnetic Iron Oxide2013
Author(s)
Satomi, T., Ogawa, M., Mori, I., Ishino, S., Kubo, K., Magata, T., & Nishimoto, T
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Journal Title
JMN
Volume: 54
Pages: 999-1004
Peer Reviewed
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[Journal Article] Migration of mouse-induced pluripotent stem cells to 図5.皮下及び内臓脂肪移植後のレポーター光シグナルの経時的変化 glioma-conditioned medium is mediated by tumor-ass0ciated specific growth factors.2011
Author(s)
Koizumi, S., Gu, C., Amano, S., Yamamoto,S., Ihara, H., Tokuyama, T., and Namba, H.
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Journal Title
ONCOLOGY LETTERS
Volume: 2
Pages: 283-288
Peer Reviewed
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