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2012 Fiscal Year Final Research Report

The study of application of microRNA to radiation therapy

Research Project

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Project/Area Number 23659603
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Radiation science
Research InstitutionNational Cancer Center Japan

Principal Investigator

ZENDA Sadamoto  独立行政法人国立がん研究センター, 臨床開発センター, 研究員 (30466198)

Co-Investigator(Kenkyū-buntansha) OMURA Motoko  横浜市立大学, 大学院・医学研究科, 客員准教授 (70244506)
HARA Takamitsu  福島県立医科大学, 医学部, 准教授 (70464542)
Project Period (FY) 2011 – 2012
KeywordsmicroRNA
Research Abstract

MicroRNA is the cellular RNA which was identified controlling expression of protein at a translation level in late years. There are many unknown parts about the function. However, some microRNAs about radiosensitivity of the cell are reported, and it is thought that new knowledge about the biological influence of the radiation may be provided if relations with microRNA and the radiosensitivity are analyzed in detail. It was thought that some microRNAs concerned radiosensitivity from the result of this study.

  • Research Products

    (4 results)

All 2012 2011 Other

All Journal Article (1 results) (of which Peer Reviewed: 1 results) Presentation (2 results) Remarks (1 results)

  • [Journal Article] Impact of early radiological response evaluation on radiotherapeutic outcomes in the patients with nasal cavity and paranasal sinus malignancies.2012

    • Author(s)
      Hojo H, Zenda S, Akimoto T, Kohno R, Kawashima M, Arahira S, Nishio T, Tahara M, Hayashi R, Sasai K
    • Journal Title

      J Radiat Res

      Volume: 53(5) Pages: 704-9

    • DOI

      doi:10.1093/jrr/rrs021

    • Peer Reviewed
  • [Presentation] Proton Beam Therapy for Patients with Malignancies of The Nasal Cavity, Para-nasal Sinuses, and/or Involving The Skull Base2011

    • Author(s)
      S Zenda
    • Organizer
      The Analysis of Late Toxicity, American Society for Radiation Oncology(ASTRO)
    • Place of Presentation
      Miami
    • Year and Date
      20111000
  • [Presentation] ワークショップ頭頸部癌治療-最新の知見―2011

    • Author(s)
      全田貞幹
    • Organizer
      第36回日本外科系連合学会学術集会
    • Place of Presentation
      浦安
    • Year and Date
      20110600
  • [Remarks]

    • URL

      http://www.ncc.go.jp/jp/ncce/rcio/research/ptd/szenda.html

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Published: 2014-09-25   Modified: 2015-11-26  

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