2012 Fiscal Year Final Research Report
Liver regeneration using stem cells from hteeth (SHED) for congenital metabol
| Project/Area Number |
23659618
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
General surgery
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| Research Institution | Kyushu University |
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Principal Investigator |
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| Project Period (FY) |
2011 – 2012
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| Keywords | 移植外科学 / 肝細胞移植 / 乳歯幹細胞 / 立体物 / 免疫寛容 |
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| Research Abstract |
SHED was shown to have the character of MSC as well as HSC. SHED low expression of HLA. SHED was successfully induced to the hepatocyte-like cell in medium. These hepatocyte-like cells were settled to the damaged liver tissue in CCl4 induced liver chirrhosis as well as Wilson disease. These cells could compose the sphere structure. On the other hand, 3D liver structure was built using 3D bioprinter.
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