Development of a method to non-invasively measure the brain temperature using diffusion tensor imaging

2012 Fiscal Year Final Research Report

• Project/Area Number: 23659696
• Research Category: Grant-in-Aid for Challenging Exploratory Research
• Allocation Type: Multi-year Fund
• Research Field: Cerebral neurosurgery
• Research Institution: Iwate Medical University
• Principal Investigator: OGAWA Akira 岩手医科大学, 学長 (10204067)
• Co-Investigator(Kenkyū-buntansha): FUJIWARA Shunrou 岩手医科大学, 医学部, 助教 (60405842) ; OGASAWARA Kuniaki 岩手医科大学, 医学部, 教授 (00305989)
• Project Period (FY): 2011 – 2012
• Keywords: 脳血管障害学 / 脳循環代謝 / MRI

Research Abstract

In this study, we aimed to develop a new method to detect the abnormality in cerebral metabolism using brain temperature calculated from diffusion tensor parameters and validate the possibility in the measurement. Our results agree withthe follo wing two hypotheses: 1) the brain temperature in patient who showed cognitive impairment after CEA may be lower than that before CEA, 2) the brain temperature in patient who showed improvement of cognition after CEA may be higher than that before CEA. Our research presented the availability of the brain temperature measured by diffusion tensor imaging in higher strength of magnetic fields for detecting the abnormality of cerebral metabolism.

Research Products

• [Journal Article] Postoperative Changes in Cerebral Metabolites Associated with Cognitive Improvement and Impairment after Carotid Endarterectomy: A 3T Proton MR Spectroscopy Study (2013)
  • Author(s): Saito H, Ogasawara K , Nishimoto H, Yoshioka Y, Murakami T, Fujiwara S, Sasaki M, Kobayashi M, Yoshida K, Kubo Y, Beppu T, Ogawa A
  • Journal Title: AJNR Am J Neuroradiol Volume: 34(5) Pages: 976-82
  • DOI: DOI:10.3174/ajnr.A3344
  • Peer Reviewed
• [Journal Article] Postoperative cerebral white matter damage associated with cerebral hyperperfusion and cognitive impairment after carotid endarterectomy: a diffusion tensor magnetic resonance imaging study (2012)
  • Author(s): Nanba T, Ogasawara K , Nishimoto H, Fujiwara S, Kuroda H, Sasaki M, Kudo K, Suzuki T, Kobayashi M, Yoshida K, Ogawa A
  • Journal Title: Cerebrovasc Dis Volume: 34 Pages: 358-67
  • DOI: DOI:10.1159/000343505
  • Peer Reviewed
• [Journal Article] Detecting damaged regions of cerebral white matter in the subacute phase after carbon monoxide poisoning using voxel-based analysis with diffusion tensor imaging (2012)
  • Author(s): Fujiwara S, Beppu T, Nishimoto H, Sanjo K, Koeda A, Mori K, Kudo K, Sasaki M, Ogasawara K
  • Journal Title: Neuroradiology Volume: 54 Pages: 681-689
  • DOI: DOI:10.1007/s00234-011-0958-8
  • Peer Reviewed
• [Presentation] 高分解能DTI tractographyを用いた三叉神経通における拡散異常の検出 (2012)
  • Author(s): 藤原俊朗
  • Organizer: 第14回日本脳神経減圧術学会
  • Place of Presentation: 東京(東京ステーションコンファレンス)
  • Year and Date: 2012-01-19
• [Remarks] 岩手医科大学医歯薬総合研究所
  • URL: http://amrc.iwate-med.ac.jp/modules/contents/index.php?content_id=81