Study of Coculture System of Vascular Endothelial Cells and Bone Marrow cells

2012 Fiscal Year Final Research Report

• Project/Area Number: 23659733
• Research Category: Grant-in-Aid for Challenging Exploratory Research
• Allocation Type: Multi-year Fund
• Research Field: Orthopaedic surgery
• Research Institution: National Institute of Advanced Industrial Science and Technology
• Principal Investigator: UEMURA Toshimasa 独立行政法人産業技術総合研究所, ナノシステム研究部門, 上級主任研究員 (60176641)
• Project Period (FY): 2011 – 2012
• Keywords: 骨再生 / 血管内皮細胞 / 骨髄細胞

Research Abstract

Tissue-engineered bone has attracted much attention as an alternative material for bone grafting; however, implantable bone tissue of an appropriate size and shape for clinical use has not yet been developed due to a lack of vascularization, which results

Research Products

• [Journal Article] Engineered bone tissue associated with vascularization utilizing a rotating wall vessel bioreactor (2013)
  • Author(s): Masanori Nishi, Rena Matsumoto, Jian Dong, Toshimasa Uemura
  • Journal Title: J Biomed Mater Res A Volume: 101(2) Pages: 421-427
• [Journal Article] Effects of implantation of three-dimensional engineered bone tissue with a vascular-like structure on repair of bone defects (2012)
  • Author(s): Masanori Nishi, Rena Matsumoto, Jian Dong, Toshimasa Uemura
  • Journal Title: Applied Surface Science Volume: 262 Pages: 60-63
• [Journal Article] Regeneration of Bone Tissue in a Controlled in VitroEnvironment with a Rotating Wall Vessel Bioreactor (2011)
  • Author(s): Masanori NISHI, Rena MATSUMOTO, Jian DONG, Toshimasa UEMURA
  • Journal Title: Nano Biomedicine Volume: 3(2) Pages: 267-274
• [Presentation] RWV微小重力培養を用いた3 次元組織の構築と再生医療 (2013)
  • Author(s): 植村寿公
  • Organizer: 第25回バイオエンジニアリング講演会
  • Year and Date: 2013-01-09
• [Presentation] RWVバイオリアクターによる擬微小重力培養法を用いた 3 次元硬組織の再生技術 (2012)
  • Author(s): 植村寿公
  • Organizer: 日本再生歯科医療学会設立10周年記念セミナー
  • Place of Presentation: 兵庫県
  • Year and Date: 2012-09-02
• [Book] Cartilage Regeneration from Bone Marrow Cells and its Automation System for Clinical Application, TISSUE ENGINEERING FOR TISSUE AND ORGAN REGENERATION ed by Daniel Eberli (2011)
  • Author(s): Toshimasa Uemura, Masanori Nishi,Kunitomo Aoki, Takashi Tsumura
  • Total Pages: 216-222
  • Publisher: INTECH