2013 Fiscal Year Final Research Report
Analysis of urethral function through visualization of urethral urine stream
| Project/Area Number |
23659753
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Urology
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| Research Institution | Chiba University |
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Principal Investigator |
IGARASHI Tatsuo 千葉大学, フロンティア医工学センター, 教授 (70302544)
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| Co-Investigator(Renkei-kenkyūsha) |
YU Wenwei 千葉大学, フロンティア医工学センター, 教授 (20312390)
RYU Hiroshi 千葉大学, 大学院工学研究科, 教授 (40303698)
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| Project Period (FY) |
2011 – 2013
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| Keywords | 排尿生理学 / 数値流体力学 / シミュレーション / 立体画像 / 内視鏡 |
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| Research Abstract |
Relationship between deformation of the male prostatic urethra and alteration of urine flow in the urethra was studied using computational flow dynamics (CFD). Since estimation of elasticity of urethral wall by assessing its vibration under irrigation had failed during the study period, urine flow simulation was performed using the solid model of the urethra. Calculation using bladder outlet (BO) obstruction model revealed size of the BO directly altered dynamics and energy loss of urine flow in the prostatic urethra. Energy loss of the urine flow was studied using 3D virtual prostatic urethra processed from endoscopic video image in patients with benign prostate hyperplasia around administration of alpha-1 adrenoceptor antagonists. The energy loss, provoked by deformation of urethra, revealed to correlate with some parameters of voiding function. The study showed usefulness of CFD in assessing urethral function in patients with voiding dysfunction.
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