2011 Fiscal Year Final Research Report
Narrowing of strabismus susceptibility loci by SNP analysis using family members
| Project/Area Number |
23659811
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Ophthalmology
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| Research Institution | Okayama University |
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Principal Investigator |
MATSUO Toshihiko 岡山大学, 大学院・医歯薬学総合研究科, 准教授 (90211565)
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| Project Period (FY) |
2011
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| Keywords | 眼遺伝学 / SNP / 斜視 / 遺伝子座 |
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| Research Abstract |
We analyzed 400 SNPs in two chromosomal loci, 4q28. 3 and 7q31. 2, which were discovered by our previous studies. The SNPs were typed with mass array in the Central Research Laboratories of Okayama University Medical School. We divided families members into two groups : patients with strabismus and other members with no diseases and compared the SNPs to find the significant difference between the two groups.
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