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2012 Fiscal Year Final Research Report

In vivo recording of brain temperatures from multiple site in mice.

Research Project

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Project/Area Number 23659871
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Functional basic dentistry
Research InstitutionOsaka University

Principal Investigator

NAKAMURA Wataru  大阪大学, 大学院・歯学研究科, 特任准教授 (60372257)

Research Collaborator NAKAMURA Takahiro  帝京平成大学, 薬学部, 講師 (00581985)
TAKASU Nana  京都大学, 医学系研究院, 日本学術振興会特別研究員(PD) (30467394)
UCHIDA Hitosi  大阪大学, 大学院・歯学研究科, 特別研究員(DC2)
Project Period (FY) 2011 – 2012
Keywords脳温 / マウス / in vivo 記録 / サーカディアンリズム研究分野
Research Abstract

The core body temperature and the peripheral one are distinct parameters in physiological function. In this study, circadian variations of deep brain temperature were recorded in freely moving mice. Micro thermistor probes were inserted aiming either into unilateral hypothalamus and the surface in cortex. Brain temperatures were recorded from freely moving mice with wheel running activity. In parallel to nocturnal activity in behavior, circadian variation of brain temperature was clarified. Furthermore, an ultradian variation was obvious as well.:

  • Research Products

    (15 results)

All 2013 2012 2011 Other

All Journal Article (9 results) (of which Peer Reviewed: 6 results) Presentation (5 results) Remarks (1 results)

  • [Journal Article] In vivomonitoring of multi-unit neural activity in the suprachiasmatic nucleus reveals robust circadian rhythms in period1^<-/-> mice.2013

    • Author(s)
      Takasu NN, Pendergast JS, Olivas CS, Yamazaki S, Nakamura W.
    • Journal Title

      PLoS One

      Volume: 8(5) Pages: e64333

    • DOI

      doi:10.1371/journal.pone.0064333

    • Peer Reviewed
  • [Journal Article] Circadian regulation of food-anticipatory activity in molecular clock-deficient mice.2012

    • Author(s)
      Takasu NN, Kurosawa G, Tokuda IT, Mochizuki A, Todo T, Nakamura W.
    • Journal Title

      PLoS ONE.

      Volume: 7(11) Pages: e48892

    • DOI

      doi:10.1371/journal.pone.0048892

    • Peer Reviewed
  • [Journal Article] Effects of age-related dopaminergic neuron loss in the substantia nigra on the circadian rhythms of locomotor activity in mice2012

    • Author(s)
      Tanaka M, Yamaguchi E, Takahashi M, Hashimura K, Shibata T, Nakamura W, Nakamura TJ
    • Journal Title

      Neurosci. Res

      Volume: 74(3-4) Pages: 210-215

    • DOI

      doi:10.1016/j.neures.2012.09.005

    • Peer Reviewed
  • [Journal Article] Suprachiasmatic nucleus: cellular clocks and networks2012

    • Author(s)
      Honma S, Ono D, Suzuki Y, Inagaki N, Yoshikawa T, Nakamura W, Honma K
    • Journal Title

      Prog Brain Res.

      Volume: 199 Pages: 129-41

    • DOI

      doi:10.1016/B978-0-444-59427-3.00029-0.

    • Peer Reviewed
  • [Journal Article] 概日時計による生体制御と消化器機能2012

    • Author(s)
      中村 渉
    • Journal Title

      Gastrointestinal Research.

      Volume: 20 Pages: 389-394

  • [Journal Article] 睡眠・覚醒・摂食行動の概日リズム制御.2012

    • Author(s)
      中村 渉
    • Journal Title

      BRAIN and NERVE.

      Volume: 64(6) Pages: 647-656

  • [Journal Article] 食事前行動のサーカディアンリズム制御機構2012

    • Author(s)
      中村 渉
    • Journal Title

      自律神経.

      Volume: 49(2) Pages: 59-62

  • [Journal Article] Importance of regular lifestyle with daytime bright light exposure on circadian rhythm sleep-wake disorders in pervasive developmental disorders.2011

    • Author(s)
      Takasu NN, Toichi M, Nakamura W.
    • Journal Title

      Jpn. Dent. Sci. Rev.

      Volume: 47(2) Pages: 141-149

    • DOI

      doi.org/10.1016/j.jdsr.2011.04.001

    • Peer Reviewed
  • [Journal Article] Age-Related Decline in Circadian Output2011

    • Author(s)
      Nakamura TJ, Nakamura W, Yamazaki S, Kudo T, Cutler T, Colwell CS, Block GD
    • Journal Title

      J Neurosci

      Volume: 31(28) Pages: 10201-10205

    • DOI

      doi:10.1523/JNEUROSCI.0451-11.2011

    • Peer Reviewed
  • [Presentation] 時計遺伝子 KO マウスの給餌予知行動サーカディアンリズム制御機構2012

    • Author(s)
      中村渉
    • Organizer
      第35回日本分子生物学会ワークショップ『概日リズムの発振と制御の分子ネットワーク』
    • Place of Presentation
      福岡
    • Year and Date
      20121211-14
  • [Presentation] げっ歯類の食事サイクル同調の特徴と性質2012

    • Author(s)
      中村渉
    • Organizer
      第19回日本時間生物学会『末梢臓器振動体の臓器特異性、同調、相互作用』
    • Place of Presentation
      北海道
    • Year and Date
      20120915-16
  • [Presentation] 体内時計神経回路の加齢変化2012

    • Author(s)
      中村渉
    • Organizer
      第5回東京アンチエイジングアカデミー
    • Place of Presentation
      東京
    • Year and Date
      2012-06-21
  • [Presentation] 体内時計中枢・視交叉上核の機能的入出力と概日行動リズム制御機構2012

    • Author(s)
      中村渉
    • Organizer
      第117回日本解剖学会
    • Place of Presentation
      山梨
    • Year and Date
      2012-03-26
  • [Presentation] 食事前行動のサーカディアンリズム制御機構2011

    • Author(s)
      中村渉
    • Organizer
      第64回日本自律神経学会総会
    • Place of Presentation
      秋田
    • Year and Date
      20111027-28
  • [Remarks]

    • URL

      http://web.dent.osaka-u.ac.jp/~chrono/

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Published: 2014-09-25  

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