2012 Fiscal Year Final Research Report
Evaluation of regions related to pain sensitization in the central nervous system for fibromyalgia patients using fMRI
| Project/Area Number |
23659904
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Prosthetic dentistry
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| Research Institution | Kyushu University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
YOSHUIUA Takashi 九州大学, 大学院・歯学研究院, 准教授 (40322747)
NAKAMURA Yasuhiko 九州大学, 大学病院, 診療放射線技師長 (00380494)
KOYANO Kiyoshi 九州大学, 大学院・歯学研究院, 教授 (50195872)
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| Project Period (FY) |
2011 – 2012
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| Keywords | fMRI / 線維筋痛症 / 筋筋膜痛 / 慢性疼痛 / 痛覚過敏 |
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| Research Abstract |
Six fibromyalgia and seven sever myofascial pain patients, and six healthy volunteers participated in this study. Measurement of functional magnetic resonance imaging (fMRI)for the whole brain was carried out before and after the therapeutic intervention, i.e., insertion of oral splint device. The analysis of fMRI data revealed that some patients exhibited the increased brain activities in primary somatosensory area, secondary somatosensory area, cingulate gyrus, and midbrain regions.
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