2012 Fiscal Year Final Research Report
A study of a synthetic construct for bone development
| Project/Area Number |
23659909
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Dental engineering/Regenerative dentistry
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| Research Institution | Tohoku University |
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Principal Investigator |
SUZUKI Osamu 東北大学, 大学院・歯学研究科, 教授 (60374948)
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| Co-Investigator(Kenkyū-buntansha) |
SHIMAUCHI Hidetoshi 東北大学, 大学院・歯学研究科, 教授 (70187425)
KAMAKURA Shinji 東北大学, 大学院・医工学研究科, 教授 (80224640)
ANADA Takahisa 東北大学, 大学院・歯学研究科, 准教授 (30398466)
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| Project Period (FY) |
2011 – 2012
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| Keywords | 石灰化球 / タンパク質 / 骨再生 |
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| Research Abstract |
Synthetic calcium phosphates, having a higher adsorption affinity with non-collagenous proteins, such as albumin, were prepared as a source material for an implantable construct. Fluoride-containing calcium phosphates, showing a relatively higher solubility and a higher protein adsorption affinity, were developed. Natural polymer, such as alginate, was used to study for the preparation of the implantable gel form.
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