2013 Fiscal Year Final Research Report
Evaluation of mechanical property by preferential alignment of biological apatite in human mandible
| Project/Area Number |
23659925
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Dental engineering/Regenerative dentistry
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| Research Institution | Tokyo Dental College |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
MATSUNAGA Satoru 東京歯科大学, 歯学部, 講師 (70453751)
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| Project Period (FY) |
2011 – 2013
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| Keywords | 生体アパタイト / ヒト顎骨 / 結晶配向性 / メカニカルストレス / 咬合 / ヤング率 |
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| Research Abstract |
Biological apatite (BAp) crystallite c-axis alignment is known to be a factor in the mechanical function of bone. This study aimed to elucidate the relationship between BAp crystallite alignment and Young's modulus in the alveolar area and base of the mandible area in human mandible cortical bone. A microbeam X-ray diffraction system was used to determine BAp crystallite alignment along the mesiodistal direction (longitudinal axis). Young's modulus along the mesiodistal direction in the same sites was also measured with nanoindentation, and the relationship between BAp crystallite alignment and Young's modulus was examined.
The present study suggests a close relationship between BAp crystallite alignment and Young's modulus, suggesting the importance of determining BAp crystallite alignment when evaluating bone strength. Determination of BAp crystallite alignment at first molar in the human mandible may also be useful in examining the effects of occlusal force.
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