2012 Fiscal Year Final Research Report
Salivary gland regeneration using titanium fiber scaffold.
| Project/Area Number |
23659955
|
|---|
| Research Category |
Grant-in-Aid for Challenging Exploratory Research
|
| Allocation Type | Multi-year Fund |
|---|
| Research Field |
Surgical dentistry
|
|---|
| Research Institution | Yokohama City University |
|---|
Principal Investigator |
AOKI Shinjiro 横浜市立大学, 医学研究科, 客員研究員 (50231759)
|
|---|
| Co-Investigator(Kenkyū-buntansha) |
HIROTA Makoto 横浜市立大学, 医学部, 准教授 (20347305)
|
|---|
| Project Period (FY) |
2011 – 2012
|
| Keywords | 唾液腺再生 / チタンファイバースキャホールド |
|---|
| Research Abstract |
The aim of this study was evaluation of the salivary gland regeneration properties of titanium fiber scaffold (TFS) that had been coated with a thin hydroxyapatite (HA) layer. Rat submandibular gland cells seeded on the hydroxyapatite coated scaffold showed higher cell attachment and proliferation activity. But, cell differentiation as well as tissue reconstitution were not seen on that scaffold. To archive tissue reconstitution of salivary gland cell, many kind of factors should be considered in further study.
|
