2013 Fiscal Year Final Research Report
Decoding internal brain dynamics by multi-scale brain model
| Project/Area Number |
23680024
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| Research Category |
Grant-in-Aid for Young Scientists (A)
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| Allocation Type | Single-year Grants |
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| Research Field |
Sensitivity informatics/Soft computing
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| Research Institution | The University of Tokyo |
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Principal Investigator |
KIYOSHI Kotani 東京大学, 新領域創成科学研究科, 准教授 (00372409)
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| Project Period (FY) |
2011-04-01 – 2014-03-31
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| Keywords | 脳波 / ニューロン / 視床ー皮質モデル |
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| Research Abstract |
In this study we proposed multi-scale brain model and developed its analytical treatments.
We analyzed a model of neuronal population and derived the corresponding Fokker-Planck equation. Analytical considerations by this equation linked microscopic neuronal properties and their macroscopic behavior. We further developed reduction methods for delay differential equations and derived analytical representation of macroscopic brain rhythms due to cortico-thalamic interactions. We also developed a model-based method that evaluated internal cortico-thalamic dynamics from noninvasive brain measurements. Then we showed the proposed method is effective for sleep stage identification.
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