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2014 Fiscal Year Final Research Report

How is cardiac parasympathetic nerve activity controlled during exercise?

Research Project

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Project/Area Number 23680067
Research Category

Grant-in-Aid for Young Scientists (A)

Allocation TypeSingle-year Grants
Research Field Sports science
Research InstitutionNational Cardiovascular Center Research Institute

Principal Investigator

TSUCHIMOCHI Hirotsugu  独立行政法人国立循環器病研究センター, 研究所, 室長 (60379948)

Project Period (FY) 2011-04-01 – 2015-03-31
Keywords運動 / 心臓 / 迷走神経 / 心拍数
Outline of Final Research Achievements

The main purpose of this study was to examine how parasympathetic nerve activity to the heart is controlled during dynamic exercise in conscious animals. In addition to this, it was also aimed to establish how to measure cardiac and hemodynamic parameters which will be affected by cardiac autonomic nervous system during dynamic exercise. Although efferent thoracic parasympathetic nerve activity could be measured successfully in anesthetized rats and mice and decerebrated-unanesthetized rats, it remains to be established how the efferent cardiac parasympathetic nerve activity can be separated from another non-cardiac parasympathetic activities. Also, because the same technical problem remains to be solved in conscious animal preparations, only mixed efferent thoracic nerve activities could be measured at this time. In the meantime, it was established to measure cardiac and hemodynamic parameters during treadmill exercise as well as during resting in conscious rats.

Free Research Field

Exercise Physiology

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Published: 2016-06-03  

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