2012 Fiscal Year Final Research Report
in vitro artificial extracellular microenvironments to investigate the mechanisms of cell regulations
Project/Area Number |
23681028
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Research Category |
Grant-in-Aid for Young Scientists (A)
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Allocation Type | Single-year Grants |
Research Field |
Microdevices/Nanodevices
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Research Institution | Kyoto University |
Principal Investigator |
KAMEI Ken-ichiro 京都大学, 物質-細胞統合システム拠点, 特定拠点助教 (00588262)
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Project Period (FY) |
2011 – 2012
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Keywords | マイクロバイオシステム / ヒト ES/iPS 細胞 / 細胞外微小環境 |
Research Abstract |
Cells in a body or tissues are placed in cellular microenvironments, and regulated their functions as well as fate decision in a highly regulated manner. In this study, I tried to create artificial cellular microenvironments with microfluidic and nanotechnologies to establish a new regulatory system for human pluripotent stem cells (hPSCs). The obtained results and findings will contribute the advancement of regenerative medicine and drug development using hPSCs.
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[Presentation] Electrospun nanofibers for creating artificial cellular microenvironments for culturing mouse embryonic stem cells2011
Author(s)
L. Liu, Q. Yuan, J. Shi, X. Li, D. Jung, L. Wang, K. Yamauchi, N. Nakatsuji, K. Kamei, Y. Chen
Organizer
2nd Nanotoday Conference
Place of Presentation
Hawaii, USA
Year and Date
20111211-15
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[Presentation] Quantitative Cytological Feature Analysis by Microfluidic Image Cytometry Reveals Phenotypic Differences among Human Pluripotent Stem Cell Lines2011
Author(s)
K. Kamei, M. Ohashi, N. Graham, L. Liu, Q. Yuan, A. T. Clark, O.N. Witte, T. G. Graeber, A. D. Pyle, N. Nakatsuji, Y. Chen and H.-R. Tseng
Organizer
9th International Society of Stem Cell Research (ISSCR) Annual Meeting
Place of Presentation
Toronto, Canada
Year and Date
20110000
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[Remarks] 亀井 謙一郎、古川 修平「ナノバイオテクノロジーが創出する学際融合研究の場: 6th Annual Symposium on Nanobiotechnology 」実験医学 , 31(3), 592-595 (2013)
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[Remarks] 亀井 謙一郎「ナノメディシン:ナノ粒子の臨床応用に向けて」実験医学, 30(12), 1928-1929 (2012)
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