Structural modification of chiral organic ion-pair for the development of stereoselective catalytic transformations

2014 Fiscal Year Final Research Report

• Project/Area Number: 23685018
• Research Category: Grant-in-Aid for Young Scientists (A)
• Allocation Type: Single-year Grants
• Research Field: Synthetic chemistry
• Research Institution: Nagoya University
• Principal Investigator: URAGUCHI Daisuke 名古屋大学, 工学(系)研究科(研究院), 准教授 (70426328)
• Project Period (FY): 2011-04-01 – 2015-03-31
• Keywords: 有機分子触媒

Outline of Final Research Achievements

This program was performed for the development of synergistic catalysis of an organic cation and an organic anion. Intermolecular ion-pairs such as chiral phosphonium aryloxide-arylhydroxide assemblies showed extraordinary high performance in a stereo- and regio-selective 1,6-addition reaction. On the other hand, intramolecular ion-pairs, chiral ammonium betaines, were found to be a key catalyst for accomplishing a series of highly stereoselective aza-Henry reactions of unsaturated nitroalkanes.

Free Research Field

有機合成化学