Development of 4-dimensional in-vivo dosimetry for proton beam therapy and application to a precise 4-dimensional proton beam treatment

2014 Fiscal Year Final Research Report

• Project/Area Number: 23689058
• Research Category: Grant-in-Aid for Young Scientists (A)
• Allocation Type: Single-year Grants
• Research Field: Radiation science
• Research Institution: National Cancer Center Japan
• Principal Investigator: KOHNO Ryosuke 独立行政法人国立がん研究センター, その他部局等, 研究員 (20392227)
• Project Period (FY): 2011-04-01 – 2015-03-31
• Keywords: 陽子線治療 / 体内線量測定 / モンテカルロ法 / GPGPU / ４次元CT / MOSFET検出器 / ４次元位置検出器

Outline of Final Research Achievements

We achieved a high accuracy and high speed of dose calculation for proton beam therapy. In order to evaluate body motion, performance of 4-dimensional CT was evaluated, and we examined operation method of the 4-dimensional CT. With the aim of high-precision in-vivo proton dosimetry, in-vivo dosimetry was performed by using a 4-dimensional position sensor and a MOSFET detector. We could successfully control the uncertainty of the measurement position by using the 4-dimensional position sensor within 1 mm for in-vivo proton dosimetry.

Free Research Field

医学物理学