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2012 Fiscal Year Final Research Report

Neural and genetic bases of higher cognitive functions and their plasticity

Research Project

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Project/Area Number 23700306
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Cognitive science
Research InstitutionTohoku University

Principal Investigator

TAKEUCHI Hikaru  東北大学, 加齢医学研究所, 准教授 (50598399)

Project Period (FY) 2011 – 2012
Keywords高次認知機能 / 神経系 / 脳イメージング / 可塑性 / 認知訓練
Research Abstract

We investigated the neural mechanisms of individual differences of higher order cognitive functions and effects of higher order cognitive training on neural mechanisms. Through longitudinal studies, we revealed the effects of training on processing speed and training on working memory. Through cross-sectional studies, we revealed neural mechanisms underlying individual differences of higher cognitive functions such as working memory, general intelligence, and creativity as well as cognitive measures that play importantroles in psychiatric disorders and subjective well-being.

  • Research Products

    (18 results)

All 2013 2012 2011

All Journal Article (16 results) (of which Peer Reviewed: 15 results) Presentation (2 results)

  • [Journal Article] White matter structures associated with empathizing and systemizing inyoung adults2013

    • Author(s)
      Takeuchi H, Taki Y, Thyreau B, Sassa Y, Hashizume H, Sekiguchi A, Nagase T, Nouchi R, Fukushima A, Kawashima R
    • Journal Title

      Neuroimage

      Volume: 77(15) Pages: 222-236

    • URL

      http://dx.doi.org/10.1016/j.neuroimage.2013.04.004

    • Peer Reviewed
  • [Journal Article] Anatomical correlates of quality of life: Evidence from voxel-based morphometry2013

    • Author(s)
      Takeuchi H, Taki Y, Nouchi R, Hashizume H, Sassa Y, Sekiguchi A, Kotozaki Y, Nakagawa S, Nagase T, Miyauchi CM, Kawashma R
    • Journal Title

      Human Brain Mapping

      Volume: (In press)

    • URL

      http://dx.doi.org/10.1002/hbm.22294

    • Peer Reviewed
  • [Journal Article] Anatomical correlates of self-handicapping tendency2013

    • Author(s)
      Takeuchi H, Taki Y, Nouchi R, Hashizume H, Sekiguchi A, Kotozaki Y, Nakagawa S, Miyauchi CM, Sassa Y, Kawashima R
    • Journal Title

      Cortex

      Volume: 49(4) Pages: 1148-1154

    • URL

      http://dx.doi.org/10.1016/j.cortex.2013.01.014

    • Peer Reviewed
  • [Journal Article] White matter structures associated with emotional intelligence: evidence from diffusion tensor imaging2013

    • Author(s)
      Takeuchi H, Taki Y, Sassa Y, HashizumeH, Sekiguchi A, Nagase T, Nouchi R, Fukushima A, Kawashima R
    • Journal Title

      Human Brain Mapping

      Volume: 34(5) Pages: 1025-1034

    • URL

      http://dx.doi.org/10.1002/hbm.21492

    • Peer Reviewed
  • [Journal Article] Regional gray matter density is associated with achievement motivation: evidence from voxel-based morphometry2012

    • Author(s)
      Takeuchi H, Taki Y, Nouchi R, Sekiguchi A, Kotozaki Y, Miyauchi CM, Yokoyama R, Iizuka K, Hashizume H, Nakagawa S, Kunitoki K, Sassa Y, Kawashima R
    • Journal Title

      Brain Structure and Function

      Volume: (In press)

    • URL

      http://dx.doi.org/10.1007/s00429-012-0485-3

    • Peer Reviewed
  • [Journal Article] Effects of working memory-training on functional connectivity and cerebral blood flow during rest2012

    • Author(s)
      Takeuchi H, Taki Y, Nouchi R, Hashizume H, Sekiguchi A, Kotozaki Y, Nakagawa S, Miyauchi CM, Sassa Y, Kawashima R
    • Journal Title

      Cortex

      Volume: (In press)

    • URL

      http://dx.doi.org/10.1016/j.cortex.2012.09.007

    • Peer Reviewed
  • [Journal Article] A voxel-based morphometry study of gray and white matter correlates of a need for uniqueness2012

    • Author(s)
      Takeuchi H, Taki Y, Nouchi R, Sekiguchi A, Kotozaki Y, Miyauchi CM, Yokoyama R, Iizuka K, Hashizume H, Nakagawa S, Kunitoki K, Sassa Y, Kawashima R
    • Journal Title

      Neuroimage

      Volume: 63(3) Pages: 1119-1126

    • URL

      http://dx.doi.org/10.1016/j.neuroimage.2012.08.037

    • Peer Reviewed
  • [Journal Article] Brain structures associated with executive functions during everyday events in a non-clinical sample2012

    • Author(s)
      Takeuchi H, Taki Y, Sassa Y, Hashizume H, Sekiguchi A, Fukushima A, Kawashima R
    • Journal Title

      Brain Structure and Function

      Volume: (In press)

    • URL

      http://dx.doi.org/10.1007/s00429-012-0444-z

    • Peer Reviewed
  • [Journal Article] Associations among imaging measures (2): The association between gray matter concentration and task-inducedactivation changes2012

    • Author(s)
      Takeuchi H, Taki Y, Nouchi R, Hashizume H, Sassa Y, Sekiguchi A, Kotozaki Y, Nakagwa S, Nagase T, Miyauch CM, Kawashima R
    • Journal Title

      Human Brain Mapping

      Volume: (In press)

    • URL

      http://dx.doi.org/10.1002/hbm.22167

    • Peer Reviewed
  • [Journal Article] Effects of processing speed training on cognitive functions and neural systems.(review)2012

    • Author(s)
      Takeuchi H, Kawashima R
    • Journal Title

      Reviews in the Neurosciences

      Volume: 23(3) Pages: 289-301

    • URL

      http://dx.doi.org/10.1515/revneuro-2012-0035

  • [Journal Article] The association between resting functional connectivity and creativity2012

    • Author(s)
      Takeuchi H, Taki Y, Hashizume H, Sassa Y, Nagase T, Nouchi R, Kawashima R
    • Journal Title

      Cerebral Cortex

      Volume: 22(12) Pages: 2921-2929

    • URL

      http://dx.doi.org/10.1093/cercor/bh r371

    • Peer Reviewed
  • [Journal Article] Regional gray and white matter volume associated with Stroop interference: Evidence from voxel-based morphometry2012

    • Author(s)
      Takeuchi H, Taki Y, Sassa Y, Hashizume H, Sekiguchi A, Nagase T, Nouchi R, Fukushima A, Kawashima R
    • Journal Title

      Neuroimage

      Volume: 59(3) Pages: 2899-2907

    • URL

      http://dx.doi.org/10.1016/j.neuroimage.2011.09.064

    • Peer Reviewed
  • [Journal Article] Cerebral blood flow during rest associates with general intelligence and creativity2011

    • Author(s)
      Takeuchi H, Taki Y, Hashizume H, Sassa Y, Nagase T, Nouchi R, Kawashima R
    • Journal Title

      PLoS ONE

      Volume: 6(9) Pages: e25532:1-9

    • URL

      http://dx.doi.org/10.1371/journal.p one.0025532

    • Peer Reviewed
  • [Journal Article] Verbal working memory performancecorrelates with regional white matter structures in the frontoparietal regions2011

    • Author(s)
      Takeuchi H, Taki Y, Sassa Y, Hashizume H, Sekiguchi A, Fukushima A, Kawashima R
    • Journal Title

      Neuropsychologia

      Volume: 49(12) Pages: 3466-3473

    • URL

      http://dx.doi.org/10.1016/j.neuropsy chologia.2011.08.022

    • Peer Reviewed
  • [Journal Article] Working memory training using mental calculation impacts regional gray matter of the frontal and parietal regions2011

    • Author(s)
      Takeuchi H, Taki Y, Sassa Y, HashizumeH, Sekiguchi A, Fukushima A, KawashimaR
    • Journal Title

      PLoS ONE

      Volume: 6(8) Pages: e23175:1-12

    • URL

      http://dx.doi.org/10.1371/journal.po ne.0023175

    • Peer Reviewed
  • [Journal Article] Effects of training of processing speed on neural systems2011

    • Author(s)
      Takeuchi H, Taki Y, Hashizume H, SassaY, Nagase T, Nouchi R, Kawashima R
    • Journal Title

      Journal of Neuroscience

      Volume: 31(34) Pages: 12139-12148

    • URL

      http://dx.doi.org/10.1523/JNEUROSCI.4611-09.2010

    • Peer Reviewed
  • [Presentation] Functional connectivity and higher order cognitive functions2013

    • Author(s)
      Takeuchi H
    • Organizer
      International Symposium on Computational Brain Science -Development and Aging of the Human Brain
    • Place of Presentation
      Sendai, Japan
    • Year and Date
      2013-03-26
  • [Presentation] The effects of the training of multi tasks on brain structures (Chosen for Interactive Poster)2011

    • Author(s)
      Takeuchi H, Taki Y, Nouchi R, Hashizume H, Sekiguchi A, Kotozaki Y, Nakagawa S,Miyauchi CM, Sassa Y, Kawashima R
    • Organizer
      17th Annual Meeting of the Organization for Human Brain Mapping
    • Place of Presentation
      Quebec, Canada
    • Year and Date
      2011-06-27

URL: 

Published: 2014-09-25  

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