2012 Fiscal Year Final Research Report

Tertiary structure prediction by multi-scale simulation

Research Project

Project/Area Number	23700359
Research Category	Grant-in-Aid for Young Scientists (B)
Allocation Type	Multi-year Fund
Research Field	Bioinformatics/Life informatics
Research Institution	National Institute of Advanced Industrial Science and Technology
Principal Investigator	KAMEDA Tomoshi 独立行政法人産業技術総合研究所, 生命情報工学研究センター, 主任研究員 (40415774)
Project Period (FY)	2011 – 2012
Keywords	蛋白質 / RNA / 立体構造予測 / 分子動力学(MD)
Research Abstract	We developed the coarse-grained model of RNA molecule. Our model consists of 3 type beads(P: Phosphate, S: sugar, B: Base). Using this model, we carried out molecular dynamics simulation of RNA, which predicted native tertiary structure correctly.