2013 Fiscal Year Final Research Report
Axonal regeneration via regulation of point contacts
| Project/Area Number |
23700376
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Neuroscience in general
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| Research Institution | University of Toyama |
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Principal Investigator |
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| Project Period (FY) |
2011 – 2013
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| Keywords | 細胞接着 / 脊髄損傷 / 軸索再生 / プロテオグリカン / プロテインキナーゼA / パキシリン / p21-activated kinase |
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| Research Abstract |
I previously clarified that enhancing of point contact dynamics promoted axonal regeneration in cultured system that mimicked failure of axonal regeneration in the injured central nervous system. In this study, I showed that protein kinase A, p21-activated kinase and paxillin were involved in the above regeneration mechanisms. This study proposes novel targets for axonal regeneration in spinal cord injury, etc.
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Research Products
(40 results)
