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2012 Fiscal Year Final Research Report

Analysis of NF-kB signaling in the pathogenesis of Rett syndrome

Research Project

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Project/Area Number 23700426
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Nerve anatomy/Neuropathology
Research InstitutionKeio University

Principal Investigator

KISHI Noriyuki  慶應義塾大学, 医学部, 特任助教 (30594882)

Research Collaborator OKANO Hideyuki  慶應義塾大学, 医学部, 教授 (60160694)
OKUNO Misako  慶應義塾大学, 医学部, 研究員
JEFFREY D. Macklis  ハーバード大学, 医学部, 教授
Project Period (FY) 2011 – 2012
Keywords脳発達障害
Research Abstract

In this research project, we investigated the involvement of NF-kB signaling in the pathogenesis of Mecp2-null mice by PCR array analysis. Using PCR arrays that consisted of 84 NF-kB signaling-related genes, we compared gene expression profiles between wi

  • Research Products

    (10 results)

All 2013 2012 2011

All Presentation (8 results) Book (2 results)

  • [Presentation] Identification and analysis of target genes of the Rett syndrome causative gene, Mecp2, in the cerebral cortex.2013

    • Author(s)
      Noriyuki Kishi et al.
    • Organizer
      第90回日本生理学会大会
    • Place of Presentation
      タワーホール船堀(東京都)
    • Year and Date
      2013-03-27
  • [Presentation] レット症候群モデルマーモセットの作製と解析2013

    • Author(s)
      岸憲幸,他
    • Organizer
      第2回マーモセット研究会
    • Place of Presentation
      慶應義塾大学北館(東京都)
    • Year and Date
      2013-02-28
  • [Presentation] Generation of TSC model marmoset ES cells with TALEN technology.2012

    • Author(s)
      Noriyuki Kishi, et al.
    • Organizer
      Neuroscience 2012
    • Place of Presentation
      New Orleans (USA)
    • Year and Date
      2012-10-17
  • [Presentation] 人工ヌクレアーゼを用いた自閉症モデルマーモセットの作製2012

    • Author(s)
      岸憲幸,他
    • Organizer
      第2回ゲノム編集研究会
    • Place of Presentation
      岡崎コンファレンスセンター(愛知県)
    • Year and Date
      2012-09-20
  • [Presentation] 人工ヌクレアーゼ技術の疾患研究への応用2012

    • Author(s)
      岸憲幸,他
    • Organizer
      第1回ゲノム編集研究会
    • Place of Presentation
      広島大学理学部(広島県)
    • Year and Date
      2012-02-29
  • [Presentation] Clarification of the operating principles of the neural circuits governing the human mind and themolecular mechanisms.2012

    • Author(s)
      Noriyuki Kishi, et al.
    • Organizer
      Frontiers in Primate Neuroscience Researches
    • Place of Presentation
      東京医科歯科大学(東京都)
    • Year and Date
      2012-02-23
  • [Presentation] Dysregulation of NF-kB signaling is involved in the pathogenesis of a mouse model for Rett syndrome.2011

    • Author(s)
      Noriyuki Kishi, et al.
    • Organizer
      Neuroscience 2011
    • Place of Presentation
      Washington DC (USA)
    • Year and Date
      2011-11-12
  • [Presentation] Dysregulation of NF-kB signaling is involved in the pathogenesis of a mouse model for Rett syndrome.2011

    • Author(s)
      Noriyuki Kishi, et al.
    • Organizer
      32nd Naito Conference
    • Place of Presentation
      八ヶ岳ロイヤルホテル(山梨県)
    • Year and Date
      2011-10-18
  • [Book] 細胞工学312012

    • Author(s)
      岸憲幸
    • Total Pages
      494-496
    • Publisher
      秀潤社
  • [Book] Neurogenesis in the Adult Brain II2011

    • Author(s)
      Noriyuki Kishi, et al.
    • Total Pages
      173-188
    • Publisher
      Springer-Verlag

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Published: 2014-08-29   Modified: 2014-10-07  

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