2012 Fiscal Year Final Research Report
Identification of regulators of biogenic amine signaling in C. elegans
| Project/Area Number |
23700439
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Neurochemistry/Neuropharmacology
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| Research Institution | The University of Tokyo |
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Principal Investigator |
SUO Satoshi 東京大学, 大学院・総合文化研究科, 助教 (20596845)
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| Project Period (FY) |
2011 – 2012
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| Keywords | 神経伝達物質 / 受容体 / モデル生物 / ドーパミン / オクトパミン / ニューロペプチド |
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| Research Abstract |
Biogenic amine neurotransmitters, such as dopamine, noradrenaline, and serotonin, play important roles in regulating behaviors and metabolism of animals. In this study, we used a model animal Caenorhabditis elegans to identify novel factors that regulate amine signaling and found that neuropeptide signaling regulates amine signaling. We also identified and characterized an amine neurotransmitter involved in this signaling.
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