2013 Fiscal Year Final Research Report
Detecting mechanism of tastant concentrations by a kinetic model for action potentials and generator potentials.
| Project/Area Number |
23700469
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Neurophysiology and muscle physiology
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| Research Institution | Kyushu Institute of Technology |
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Principal Investigator |
OHTUBO Yoshitaka 九州工業大学, 生命体工学研究科(研究院), 准教授 (00380725)
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| Project Period (FY) |
2011 – 2013
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| Keywords | 味蕾細胞 / 活動電位 / 電位依存性チャネル / パッチクランプ法 / single cell RT-PCR / 免疫染色法 |
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| Research Abstract |
Action potentials in taste receptor cells play an important role in taste transmissions to neighboring cells including taste nerve fibers. I show that the shape of action potentials differs among cell types and that taste bud cells express voltage-gated channels and their genes in a cell-type-dependent manner. The discussion is made on the role of these voltage-gated currents in the transmission of taste responses.
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