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2012 Fiscal Year Final Research Report

Analysis of gene expression program governing the transition from axon growth phase to synaptogenic phase

Research Project

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Project/Area Number 23700472
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Neurophysiology and muscle physiology
Research InstitutionKeio University

Principal Investigator

KUWAKO Ken-ichiro  慶應義塾大学, 医学部, 特任助教 (30468475)

Project Period (FY) 2011 – 2012
Keywords軸索伸展 / シナプス形成 / 遺伝子発現
Research Abstract

In the developing pontine neurons (PN), we identified transcription factors that were up/down-regulated in the presence of cerebellar granule cells which are target cells of PN axons. Among those transcription factors, multiple molecules showed the abilit

  • Research Products

    (6 results)

All 2013 2012 2011

All Journal Article (1 results) (of which Peer Reviewed: 1 results) Presentation (4 results) Book (1 results)

  • [Journal Article] Sox21 promotes hippocampal adult neurogenesis via the transcriptional repression of the Hes5gene.2012

    • Author(s)
      Matsuda S. ,Kuwako K., Okano H.J., Tsutsumi S., Aburatani H., Saga Y., Matsuzaki Y., Akaike A., Sugimoto H., Okano H.
    • Journal Title

      Journal of Neuroscience

      Volume: 32 Pages: 12543-12557

    • DOI

      doi:10.1523/ JNEUROSCI.5803- 11.2012

    • Peer Reviewed
  • [Presentation] Analysis of mechanism regulating synaptic specificity in cerebellar limbic system2012

    • Author(s)
      桑子賢一郎、岡野栄之
    • Organizer
      第35回日本分子生物学会
    • Place of Presentation
      福岡国際会議場・ マリンメッセ福岡
    • Year and Date
      2012-12-14
  • [Presentation] 小脳辺縁系神経回路の特異的シナプ ス結合を制御する分子の探索2012

    • Author(s)
      桑子賢一郎、岡野栄之
    • Organizer
      第35回日本神経科学会
    • Place of Presentation
      名古屋国際会議場
    • Year and Date
      2012-09-21
  • [Presentation] Screening for molecules regulating synaptic specificity in cerebellar limbic system2012

    • Author(s)
      Ken-ichiro Kuwako, Hideyuki Okano
    • Organizer
      The 4th Biennial Symposium on Brain and Mind Research in the Asia-Pacific (BMAP 2012)
    • Place of Presentation
      Tokyo, Japan
    • Year and Date
      2012-08-30
  • [Presentation] 特異的神経回路形成を担う遺伝子発現プログラムの解析2011

    • Author(s)
      桑子賢一郎、岡野栄之
    • Organizer
      第34回日本神経科学会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2011-09-17
  • [Book] 神経回路形成をつかさどる遺伝子発現プログラム2013

    • Author(s)
      桑子賢一郎 ほか 8 名
    • Total Pages
      59-82
    • Publisher
      (株)クバプロ

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Published: 2014-08-29   Modified: 2014-10-07  

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