2012 Fiscal Year Final Research Report
A study of the method of diagnosing/imaging brain tissue viability using light scattering
| Project/Area Number |
23700497
|
|---|
| Research Category |
Grant-in-Aid for Young Scientists (B)
|
| Allocation Type | Multi-year Fund |
|---|
| Research Field |
Fusional brain recording science
|
|---|
| Research Institution | 防衛医科大学校 (2012)
National Defense Medical College (2011) |
|---|
Principal Investigator |
KAWAUCHI Satoko 防衛医科大学校, 防衛医学研究センター, 助教 (20506505)
|
|---|
| Project Period (FY) |
2011 – 2012
|
| Keywords | 脳形態計測 / 光脳科学 |
|---|
| Research Abstract |
For the development of non-invasive, real-time diagnostic technique for monitoring brain tissue viability such as in stroke patients, we investigated the validity of a light-scattering-based optical method by animal experiments. We examined signal sources of light-scattering change associated with loss of brain tissue viability, and revealed the relationship between spatiotemporal change in light scattering and reversibility of the brain tissue. We also performed light-scattering imaging of peri-infarct depolarization which can be associated with expansion of infarct area. The results will provide new insight into not only diagnosis but also pathophysiology and new therapeutic approach for the stroke.
|
