2014 Fiscal Year Final Research Report
Development of electrical , chemical, and mechanical integration myocardial cell model to reproduce the micro flow of intracellular
| Project/Area Number |
23700530
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Biomedical engineering/Biological material science
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| Research Institution | Nagoya University |
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Principal Investigator |
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| Project Period (FY) |
2011-04-28 – 2015-03-31
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| Keywords | 三相理論 |
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| Outline of Final Research Achievements |
Micro flow of intracellular fluid, the cellular tissue
and ion influence mutually to show a complex phenomenon.
In this study, we examined the triphasic theory as numerical analysis method to reproduce this phenomenon . In this theory , all of the solid displacement , fluid velocity , pressure , ion current , and ion potential are unknown of coupling analysis to make the amount of calculation huge. As cells contraction is a dynamic problem, solving the simultaneous equations by splitting method is suitable for practically applying. The method can reduce substantial amount of calculation in the following three ways: by reducing unknowns of simultaneous equations; by allowing some of the equations to be solved explicitly; and by allowing some of the equations to be calculated in fine time increments.
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| Free Research Field |
有限要素法
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