2012 Fiscal Year Final Research Report
The gene expression analysis in kidney-like structure compared to Embryonic kidney and adult kidney
| Project/Area Number |
23700537
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Biomedical engineering/Biological material science
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| Research Institution | Okayama University |
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Principal Investigator |
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| Project Period (FY) |
2011 – 2012
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| Keywords | 腎臓 / 再生 / 臓器構築 / 遺伝子発現 |
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| Research Abstract |
We have succeeded to reconstitute the renal structure from renal stem/ progenitor cells in Vitro. However, it is unknown whether the gene expression in kidney-like structure from renal stem/progenitor cells, in embryonic kidney and in adult kidney is close or not. Here we performed to elucidate the concordance rate between the gene expression in kidney-like structure and the gene expression in embryonic kidney and adult kidney by DNA analysis. The gene expression of kidney-like structure was very close to the embryonic kidney, and was on the time course of kidney development. However, it should be analyze more detail.
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