2012 Fiscal Year Final Research Report
Muscle tissue construction by label-free cell assembly based on the magneto-Archimedes effect
| Project/Area Number |
23700557
|
|---|
| Research Category |
Grant-in-Aid for Young Scientists (B)
|
| Allocation Type | Multi-year Fund |
|---|
| Research Field |
Biomedical engineering/Biological material science
|
|---|
| Research Institution | Osaka University (2012)
Tokyo University of Agriculture and Technology (2011) |
|---|
Principal Investigator |
|
|---|
| Project Period (FY) |
2011 – 2012
|
| Keywords | 組織工学 / 磁気アルキメデス効果 / 細胞アセンブリ |
|---|
| Research Abstract |
In the present study, a cell assembly device for in-vitro three-dimensional (3D) tissue construction based on the magneto-Archimedes effect was designed and fabricated. So as to utilize the magneto-Archimedes effect, it is necessary to add paramagnetic compound like an MRI contrast agent to the culture medium. We confirmed that its cytotoxicity was low enough. We also aggregated myoblast cells with the developed device and tried construct a 3D muscle tissue.
|
