2013 Fiscal Year Final Research Report
Development of a thermal treatment system combined with drug-delivery imaging using a multi-functional thermo-sensitive nano-carrier
| Project/Area Number |
23700589
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Medical systems
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| Research Institution | National Institute of Radiological Sciences |
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Principal Investigator |
KOKURYO Daisuke 独立行政法人放射線医学総合研究所, 分子イメージング研究センター, 研究員 (20508543)
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| Project Period (FY) |
2011 – 2012
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| Keywords | 低侵襲治療 / 薬剤送達 / 磁気共鳴画像 / 温熱療法 |
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| Research Abstract |
The purpose of this study was to develop a thermal treatment system combined with drug-delivery imaging using a multi-functional thermo-sensitive liposome. The dynamics of the liposomes in tumor and normal tissues such as liver and kidney was evaluated using quantitative MR imaging techniques. Also, a real-time visualization system for temperature changes and treatment effects was developed and an investigation of heating in the MR scanner with an ultrasound probe was performed.
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