2012 Fiscal Year Final Research Report
Paired associative stimulation for smooth movement: change in reciprocal inhibition
| Project/Area Number |
23700633
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Rehabilitation science/Welfare engineering
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| Research Institution | Niigata University of Health and Welfare |
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Principal Investigator |
SUZUKI Makoto 新潟医療福祉大学, 医療技術学部, 講師 (80554302)
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| Project Period (FY) |
2011 – 2012
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| Keywords | 作業療法学 |
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| Research Abstract |
Paired associative stimulation (PAS) is used to induce plasticity in the human motor cortex. Although reciprocal inhibition of antagonist muscles plays a fundamental role in human movements, (a) change in reciprocal inhibition function during the motor learning process and (b) change in cortical circuits for reciprocal muscles by PAS are unknown. The results of this study implied that (a) motor skill training could induce reciprocal change in corticospinal excitability and (b) the intracortical excitability for reciprocal muscles including GABAB-ergic inhibitory systems within primary motor cortex could be differently altered by PAS.
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