2012 Fiscal Year Final Research Report
Study on the efficacy of fish-based diet in patients with diabetes mellitus.
| Project/Area Number |
23700797
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Applied health science
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| Research Institution | Shiga University of Medical Science |
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Principal Investigator |
KONDO Keiko 滋賀医科大学, 医学部, 教務補佐員 (20566567)
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| Project Period (FY) |
2011 – 2012
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| Keywords | 栄養治療 / 魚食 / 糖尿病 / 動脈硬化 |
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| Research Abstract |
Intervention with fish-based diet showed that both dietary intake and serum levels of ω-3 polyunsaturated fatty acids increased, and serum triglyceride level decreased, but not with a control diet. The fish-based diet intervention improved the vascular function assessed with the peak forearm blood flow, duration of reactive hyperaemia, and flow debt repayment. These changes were sustained even after patients discontinued the fish-based diet for 4 weeks (control diet). This study shows that a fish-based diet intervention improves vascular function. The effect was sustained for an additional 4 weeks after stopping the intervention in patients with diabetes mellitus.
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