2012 Fiscal Year Final Research Report
Comprehensive approach for the prevention of physical frailty focusing on body composition phenotypes of sarcopenia and obesity in older adults
| Project/Area Number |
23700820
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Applied health science
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| Research Institution | Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology |
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Principal Investigator |
KIM Miji 地方独立行政法人東京都健康長寿医療センター(東京都健康長寿医療センター研究所), 東京都健康長寿医療センター研究所, 研究員 (40601349)
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| Project Period (FY) |
2011 – 2012
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| Keywords | 虚弱高齢者 / サルコペニア / 肥満 |
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| Research Abstract |
We investigated the association between physiology, physical function, and body composition phenotypes (normal, sarcopenic, obese, and sarcopenic obesity [SO]) in frail elderly individuals. The hand grip strength and knee extension strength were significantly lower in the SO group than in the normal group. The SO group had significantly higher p2-microglobulin levels than the normal group, but not higher than the sarcopenic and obese groups. Moreover, the SO group spent significantly more time in sedentary behavior and less time in light physical activity than the normal group. In this study, SO was found to be more closely associated with decline in physical function and decrease in physical activity than sarcopenia or obesity alone in frail elderly individuals.
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