2012 Fiscal Year Final Research Report
ChREBP in the lifestyle related disease- The novel mechanism of ChREBP activation-
| Project/Area Number |
23700850
|
|---|
| Research Category |
Grant-in-Aid for Young Scientists (B)
|
| Allocation Type | Multi-year Fund |
|---|
| Research Field |
Applied health science
|
|---|
| Research Institution | Hyogo Medical University |
|---|
Principal Investigator |
|
|---|
| Project Period (FY) |
2011 – 2012
|
| Keywords | 生活習慣病 / ChREBP |
|---|
| Research Abstract |
The number of people who suffer from metabolic syndromes, such as overweight, hyperlipemia, diabetes, and high blood pressure. It is known that the abnormalities of sugar and lipid metabolism are participating in the pathogenic mechanism centering on these overweight. Two or more enzyme relate to these metabolism mutually and the transcription factor which promotes the expression of important enzyme especially is ChREBP. In this study, we challenged to solve the activation mechanism of ChREBP andaimed at overweight prevention and development of a curative medicine.
|
