Common bean extract intake improves lipid/carbohydratemetabolism disorder

2012 Fiscal Year Final Research Report

• Project/Area Number: 23700922
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Multi-year Fund
• Research Field: Eating habits, studies on eating habits
• Research Institution: Saitama Medical University
• Principal Investigator: SEO Makoto 埼玉医科大学, 医学部, 助教 (10406473)
• Project Period (FY): 2011 – 2012
• Keywords: いんげん豆 / 脂肪肝 / 脂質代謝 / 糖質代謝 / アディポサイトカイン

Research Abstract

High fat-induced body weight gain, liver and adipose tissue weight gain were suppressed by ingestion of common bean extract, and serum fat/carbohydrate parameters and adipocytokines concentration were also improved near by normal mice. Moreover, lipid droplet accumulation in the liver was reduced by ingestion of common bean extract. It is suggested that the mechanisms of these improvement effects may be regulated the gene expression of lipid-carbohydrate metabolism pathways and also be regulated the activation of the multiple transcriptional factors and signaling factors.