2013 Fiscal Year Final Research Report
Novel multi-omics approach for discovery of splicing variants in cancer stem cells
| Project/Area Number |
23701092
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Tumor diagnosis
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| Research Institution | Shizuoka Cancer Center Research Institute |
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Principal Investigator |
HATAKEYAMA Keiichi 静岡県立静岡がんセンター(研究所), その他部局等, 研究員 (20564157)
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| Project Period (FY) |
2011 – 2012
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| Keywords | 癌 / バイオマーカー / オミクス / がん幹細胞 / スプライシング |
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| Research Abstract |
This research aim is development of novel multi-omics approach for discovery of splicing variants in cancer stem cells. Our approach is based on transcriptomics and proteomics. Using the multi-omics analysis, we identified novel cancer-specific aberrant transcripts (splice variants) and variant-derived proteins (protein isoforms) in cancer cells and patients with cancer.
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[Presentation] Survivin expression in circulating tumor cells of patients with gastric cancer2014
Author(s)
Masanori Terashima, Keiichi Hatakeyama, Yushi Yamakawa, Norihiko Sugisawa, Yuichiro Miki, Rie Makuuchi, Hironobu Goto, Masanori Tokunaga, Yutaka Tanizawa, Etsuro Bando, Taiichi Kawamura, Keiichi Oshima and Toru Mochizuki
Organizer
2014 ASCO Gastrointestinal Cancers Symposium
Place of Presentation
San Francisco, CA
Year and Date
20140100
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[Presentation] 胃癌における新規スプライシングバリアントの臨床病理学的検討2012
Author(s)
山川雄士,谷澤豊,畠山慶一,坂東悦郎,川村泰一,徳永正則,絹笠祐介,上坂克彦,金本秀行,望月徹,寺島雅典
Organizer
第84回日本胃癌学会総会
Place of Presentation
大阪府,大阪国際会議場
Year and Date
20120200
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