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2012 Fiscal Year Final Research Report

Fabrication of epoxy-based molecular permeable membrane and analysis of membrane characteristics using coarse-grained molecular dynamics simulation

Research Project

  • PDF
Project/Area Number 23710148
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Microdevices/Nanodevices
Research InstitutionKyoto University

Principal Investigator

HIRAI Yoshikazu  京都大学, 先端医工学研究ユニット, 特定助教 (40452271)

Project Period (FY) 2011 – 2012
Keywordsリソグラフィ / 粗視化分子動力学 / 分子透過膜 / フォトレジスト / 弾性率
Research Abstract

Biocompatible permeable membranes integrated with a microfluidic system, which allow the diffusion of biological molecules with certain molecular weight, are desirable in biomedical applications. This study reports on a molecular level study of the molecules permeability of epoxy-based chemically-amplified photoresists by employing a coarse-grained molecular dynamics simulation. For analyzing mechanical property and diffusion coefficient of molecular in photoresists, Kremer-Grest model with an extended angle bending potential was employed. The simulation results show the same tendency with the experimental results, and which suggests photoresist membrane can be used as permeable membranes with controllable permeability by varying lithography parameters.

  • Research Products

    (8 results)

All 2013 2012 2011 Other

All Journal Article (3 results) (of which Peer Reviewed: 3 results) Presentation (5 results)

  • [Journal Article] Phenotypic and Transcriptional Modulation of Human Pluripotent Stem Cells Induced by Nano/Microfabrication Materials2013

    • Author(s)
      K. Kamei、Y . Hirai、M. Yoshioka、Y .Makino、Q. Yuan、M. Nakajima、Y . Chen、O. Tabata
    • Journal Title

      Advanced Healthcare Materials

      Volume: 2 Pages: 287-291

    • DOI

      DOI:10.1002/adhm.201200283

    • Peer Reviewed
  • [Journal Article] Simulation of Mechanical Properties of Epoxy-Based Chemically Amplified Resist by Coarse-Grained Molecular Dynamics2012

    • Author(s)
      H. Yagyu、Y . Hirai、A. Uesugi、Y . Makino、K. Sugano 、T . Tsuchiya 、O. Tabata
    • Journal Title

      Polymer

      Volume: 53 Pages: 4834-4842

    • DOI

      DOI:10.1016/j.polymer.2012.08.050

    • Peer Reviewed
  • [Journal Article] MEMSネガレジストの粗視化分子動力学シミュレーション

    • Author(s)
      平井義和、柳生裕聖、牧野圭秀、上杉晃生、菅野公二、土屋智由、田畑修
    • Journal Title

      電気学会論文誌E(センサ・マイクロマシン部門誌)

    • Peer Reviewed
  • [Presentation] Material Characterizations of Negative Photoresist for Bio-MEMS Applications2012

    • Author(s)
      Y . Hirai
    • Organizer
      IEEE-NMDC 2012
    • Place of Presentation
      、Hyatt Regency Waikiki Beach Resort and Spa (Hawaii、USA)(招待講演)
    • Year and Date
      2012-10-18
  • [Presentation] Investigation of Molecular Diffusivity of Photoresist Membrane using Coarse-Grained Molecular Dynamics Simulation2012

    • Author(s)
      H. Yagyu 、Y . Hirai 、Y . Makino 、K.Sugano 、T . Tsuchiya 、O. Tabata
    • Organizer
      Eurosensors XXVI
    • Place of Presentation
      Krakow Opera (Krakow、Poland)
    • Year and Date
      2012-09-11
  • [Presentation] Coarse-Grained Molecular Dynamics Simulation of Epoxy-Based Chemically-Amplified Resist for MEMS Application2011

    • Author(s)
      H. Yagyu、Y. Hirai、A. Uesugi、Y . Makino、K. Sugano 、T . Tsuchiya 、O. Tabata
    • Organizer
      2011 MRS Fall Meeting
    • Place of Presentation
      Hynes Convention Center (Boston、MA USA)
    • Year and Date
      2011-11-29
  • [Presentation] Mechanical Characterization of Negative Photoresist by Nano-Indentation for Nano-Filtration Membrane2011

    • Author(s)
      Y. Hirai、A. Uesugi、Y . Makino、H. Yagyu、K. Sugano 、T . Tsuchiya 、O. Tabata
    • Organizer
      HARMST2011
    • Place of Presentation
      Ambassador Hotel-Hsinchu Hotel (Hsinchu、Taiwan)
    • Year and Date
      2011-06-14
  • [Presentation] Negative-Photoresist Mechanical Property for Nano-Filtration Membrane Embedded in Microfluidics2011

    • Author(s)
      Y. Hirai、A. Uesugi、Y . Makino、H. Yagyu、K. Sugano 、T . Tsuchiya 、O. Tabata
    • Organizer
      Transducers'11
    • Place of Presentation
      China National Convention Center (Beijing、China)
    • Year and Date
      2011-06-08

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Published: 2014-09-25  

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