2012 Fiscal Year Final Research Report
The role of nutrition-sensitive histone demethylase in the formationof obesity-associated epigenome
| Project/Area Number |
23710226
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Medical genome science
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| Research Institution | Kumamoto University |
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Principal Investigator |
HINO Shinjiro 熊本大学, 発生医学研究所, 助教 (00448523)
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| Project Period (FY) |
2011 – 2012
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| Keywords | エピジェネティクス / ヒストン脱メチル化 / エネルギー代謝 / 肥満 |
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| Research Abstract |
T o date, we do not know how dietary habit in childhood affects the development ofobesity later in life. We identified that LSD1, a gene regulator , controls the cellularmetabolism in response to the energy overload. Our findings provide important clues forunderstanding how environmental factors influence the disease risks
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