2013 Fiscal Year Final Research Report
Molecualr dynamics study on the molecuar permeability of membrane protein
| Project/Area Number |
23750008
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Physical chemistry
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| Research Institution | Kanazawa University |
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Principal Investigator |
SAITO Hiroaki 金沢大学, 数物科学系, 助教 (40506820)
|
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| Project Period (FY) |
2011 – 2013
|
| Keywords | 分子動力学法 / 脂質二重層膜 / 膜タンパク質 / 自由エネルギー |
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| Research Abstract |
We have carried out molecular dynamics simulations to analysis the structure and dynamics of peptide and membrane protein in several lipid bilayer environments and have investigated the ion and molecular permeability through the channel of membrane protein. The thermal stability of membrane protein in the lipid bilayers has also been investigated by free energy calculation.
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Research Products
(34 results)
