2012 Fiscal Year Final Research Report
Quantitative imaging probe for hypoxia
| Project/Area Number |
23750081
|
|---|
| Research Category |
Grant-in-Aid for Young Scientists (B)
|
| Allocation Type | Multi-year Fund |
|---|
| Research Field |
Analytical chemistry
|
|---|
| Research Institution | The University of Tokyo (2012)
Kyoto University (2011) |
|---|
Principal Investigator |
KOMATSU Hirokazu 東京大学, 大学院・薬学系研究科, 特任研究員 (10407140)
|
|---|
| Project Period (FY) |
2011 – 2012
|
| Keywords | 蛍光 / りん光 / 分子プローブ / イメージング / 低酸素 / レシオ測定 / がん / ルテ ニウム錯体 |
|---|
| Research Abstract |
To diagnose cancer in earlier stage, valid imaging method is required. Hypoxia is the indicator for solid cancer. Thus, I focused on develop ‘quantitative’ imaging probe for hypoxia. Developed novel hypoxia probe showed ratiometric and reversible response to O2, successfully applied to in cell and in vivo imaging of hypoxia.
|
Research Products
(4 results)
