2013 Fiscal Year Final Research Report
Functional Polymer-Based Allosteric Chiral Snesing
| Project/Area Number |
23750129
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Polymer chemistry
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| Research Institution | Osaka University |
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Principal Investigator |
FUKUHARA Gaku 大阪大学, 工学(系)研究科(研究院), 助教 (30505996)
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| Project Period (FY) |
2011 – 2013
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| Keywords | 機能性高分子 / 生体関連高分子 / 分子認識 / 超分子 |
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| Research Abstract |
The applicant has expanded his work to polymer-based supramolecular sensing of bio-related materials. To develop a chirality sensing system based on polythiophene, a permethylated cyclodextrin was attached to monothiophene unit with a hexamethylene spacer,which was then polymerized to give novel functional polythiophenes with chirality recognition sites. The cyclodextrin-appended polythiophene showed high enantioselectivity of 13.7 for phenylalanine dipeptide.
To further achieve a more difficult task by constructing a saccharide sensor operative in aqueous media, the applicant employed polysaccharide curdlan (Cur) as a hydrogen-bonding saccharide receptor. Thus, the saccharide sensing by using native Cur/polythiophene complex hybridized in situ as a signal-amplifying reporter enabled us to selectively sense acarbose among 24 mono-, di-, tri, tetra-, and pentasaccharides.
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[Journal Article] Manipulating γ-Cyclodextrin-mediated Photocyclodimerization of Anthracenecarboxylate by Wavelength, Temperature, Solvent and Host2014
Author(s)
Yang, C.; Wang, Q.; Yamauchi, M.; Yao, J.; Zhou, D.; Nishijima, M.; Fukuhara, G.; Mori, T.; Liu, Y.; Inoue, Y
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Journal Title
Photochem. Photobiol. Sci
Volume: 13 (Special Issue)
Pages: 190-198
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[Journal Article] Diastereodifferentiating Photocyclodimerization of 2-Anthracenecarboxylates Tethered to a Cyclic Tetrasaccharide Scaffold : Critical Control of Photoreactivity and Stereoselectivity2013
Author(s)
Fukuhara, G.; Nakamura, T.; Kawanami, Y.; Yang, C.; Mori, T.; Hiramatsu, H.; Dan-oh, Y.; Nishimoto, T.; Tsujimoto, K.; Inoue, Y
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Journal Title
J. Org. Chem
Volume: 78
Pages: 10996-11006
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[Journal Article] Phase-Controlled Supramolecular Photochirogenesis in Cyclodextrin Nanosponges2013
Author(s)
Liang, W.; Yang, C.; Zhou, D.; Haneoka, H.; Nishijima, M.; Fukuhara, G.; Mori, T.; Castiglione, F.; Mele, A.; Caldera, F.; Trotta, F.; Inoue, Y
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Journal Title
Chem. Commun
Volume: 49 (Front Cover)
Pages: 3510-3512
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[Journal Article] Cyclodextrin Nanosponge-Sensitized Enantiodifferentiating Photoisomerization of Cyclooctene and 1,3-Cyclooctadiene2012
Author(s)
Liang, W.; Yang, C.; Nishijima, M.; Fukuhara, G.; Mori, T.; Mele, A.; Castiglione, F.; Caldera, F.; Trotta, F.; Inoue, Y
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Journal Title
Beilstein J. Org. Chem
Volume: 8
Pages: 1305-1311
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[Journal Article] Chiral Ionic Liquid-Mediated Photochirogenesis. Enantiodifferentiating Photocyclodimerization of 2-Anthracenecarboxylic Acid2011
Author(s)
Fukuhara, G.; Okazaki, T.; Lessi, M.; Nishijima, M.; Yang, C.; Mori, T.; Mele, A.; Bellina, F.; Chiappe, C.; Inoue, Y
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Journal Title
Org. Biomol. Chem
Volume: 9
Pages: 7105-7112
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[Journal Article] Competitive Photocyclization/Rearrangement of 4-Aryl-1,1-dicyanobutenes Controlled by Intramolecular Charge-Transfer Interaction. Effect of Medium Polarity, Temperature, Pressure, Excitation Wavelength, and Confinement2011
Author(s)
Ito, T.; Nishiuchi, E.; Fukuhara, G.; Inoue, Y.; Mori, T
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Journal Title
Photochem. Photobiol. Sci
Volume: 10 (Special Issue)
Pages: 1405-1414
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[Journal Article] Supramolecular Complexation and Photocyclodimerization of Methyl 3-Methoxy-2-naphthoate with Modified γ-Cyclodextrins2011
Author(s)
Liang, W.; Zhang, H.-H.; Wang, J.-J.; Peng, Y.; Chen, B.; Yang, C.; Tung, C.-H.; Wu, L.-Z.; Fukuhara, G.; Mori, T.; Inoue, Y
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Journal Title
Pure Appl. Chem
Volume: 83
Pages: 769-778
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[Presentation] キラルイオン液体を用いる2-アントラセンカルボン酸の光不斉反応
Author(s)
福原 学・岡崎 崇央・Lessi, M・Mele, A・Bellina, F・Chiappe, C・井上 佳久
Organizer
Collaborative Conference on Materials Research
Place of Presentation
Jeju Island
Year and Date
00000623-28
Invited
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