2013 Fiscal Year Final Research Report
Intracellular dynamics of traction forces under physiological mechanical stimulations
| Project/Area Number |
23760107
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Materials/Mechanics of materials
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| Research Institution | 防衛大学校(総合教育学群、人文社会科学群、応用科学群、電気情報学群及びシステム工学群) |
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Principal Investigator |
TSUKAMOTO Akira 防衛大学校(総合教育学群、人文社会科学群、応用科学群、電気情報学群及びシステム工, 応用科学群, 助教 (90511460)
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| Project Period (FY) |
2011 – 2012
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| Keywords | 細胞バイオメカニクス |
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| Research Abstract |
Mechanical stresses induced on our body involve in multiple disorders. In this study, in order to understand how the mechanical stresses involve in those disorders, intracellular alterations of traction force were tried to be measured. For the measurement, measuring system was developed. Moreover, as a mechanism of the alterations, cytoskeletons were considered as a mechanical model. As a result, although alterations of intracellular traction forces remain indispensable noises for valid analysis, those of cellular traction forces were valid. In addition with alterations of cytoskeletons, it was indicated that ablation of cytoskeletons induced several types of alterations in cellular traction forces.
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[Presentation] 衝撃波照射による細胞骨格牽引力変化の観察2014
Author(s)
塚本哲,中川桂一,太刀川遼,廖洪恩,小林英津子,多田茂,牛田多加志,佐久間一郎
Organizer
第26回バイオエンジニアリング講演会
Place of Presentation
東北大学(第26回バイオエンジニアリング講演会講演論文集,37-38)
Year and Date
20140100
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[Presentation] 医用衝撃波が細胞3次元培養体で惹起する細胞内Ca^<2+>上昇2013
Author(s)
垣野内壮一郎,塚本哲,中川桂一,太刀川遼,荒船龍彦,廖洪恩,小林英津子,佐久間一郎,牛田多加志,多田茂
Organizer
第25回バイオエンジニアリング講演会
Place of Presentation
産業技術総合研究所(第25回バイオエンジニアリング講演会講演論文集,89-90)
Year and Date
20130100
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